Dapagliflozin is an SGLT2 inhibitor that helps eliminate excess glucose from the body through the urine. Among the many SGLT2 inhibitors available, it is one of the most widely used drugs worldwide—not only for diabetes treatment, but also as a medication that protects the heart and kidneys.
*Dayvigo Plan: First month free+ ¥5,980/month from the second month. Cancel anytime after the 2nd delivery. *Dapagliflozin Plan: ¥4,980/month starting month 2. Cancel anytime after the 2nd delivery.
1. What Are SGLT2 Inhibitors?
A New Concept: “Protecting by Eliminating”
Conventional diabetes medications mainly work by stimulating insulin secretion or reducing glucose absorption. SGLT2 inhibitors, however, work in a completely different way.
Basic Mechanism
They block the action of SGLT2, a protein in the kidneys responsible for reabsorbing glucose. By preventing this reabsorption, excess glucose is excreted from the body in the urine, naturally lowering blood glucose levels.
Three Common Benefits of SGLT2 Inhibitors
Improved blood glucose control: Glucose is eliminated directly, without relying on insulin.
Weight loss: Approximately 200–400 kcal per day (equivalent to 1–1.5 bowls of rice) are lost through glucose excretion, leading to potential weight reduction.
Lower blood pressure: Water is excreted along with glucose, which helps reduce edema and tends to lower blood pressure.
2. Why Dapagliflozin? Three Key Features
There are several types of SGLT2 inhibitors (such as empagliflozin and canagliflozin), but dapagliflozin is often chosen because of its broad indications and strong clinical track record.
① Effective for Heart Failure and Kidney Disease Even Without Diabetes
This is its most distinctive feature. Dapagliflozin is approved for the treatment of chronic heart failure and chronic kidney disease (CKD) regardless of whether the patient has diabetes.
It is highly regarded as a drug that not only lowers blood glucose but also strongly protects vital organs in the long term.
② Approved for Use in Type 1 Diabetes
While most SGLT2 inhibitors are indicated only for type 2 diabetes, dapagliflozin is approved for use in type 1 diabetes when used in combination with insulin therapy (with certain restrictions).
③ Extensive Clinical Evidence
Large-scale global clinical trials have demonstrated that dapagliflozin reduces the risk of cardiovascular death and slows the progression of renal function decline.
How to Take
Take one tablet once daily by mouth
The timing of administration is generally flexible, though taking it at the same time each day is often recommended
Food does not significantly affect absorption, so it may be taken before or after meals
Be sure to maintain adequate hydration while taking this medication
Possible Side Effects
Increased urination or urine volume
Thirst or dry mouth
Tendency toward dehydration
Genital or urinary tract infections (itching, discomfort, pain during urination, etc.)
Hypoglycemia (especially when used with other diabetes medications)
※ Because dapagliflozin promotes glucose excretion through urine, sufficient fluid intake is important. If you experience any unusual symptoms, please consult a physician promptly.
📱 How to Receive Your Medication
[How It Works]
STEP 1: Purchase the Dapagliflozin 5mg treatment ePass on this page.
STEP 2: You will receive an email containing information about the online consultation and your ePass.
STEP 3: Click the link in the email to book your free doctor consultation through the elife website. (Please make sure to use the same email address that received the ePass when registering on elife.)
STEP 4: After your consultation, if a prescription is approved, your medication will be shipped to your home. (※Please note that depending on your questionnaire results or the doctor’s judgment, a prescription may not be issued. In that case, you will receive a full refund.)
Note: This is a private (self-paid) medical service.
※ This is a self-paid treatment (not covered by insurance in Japan).
📌 Our Strengths
✔️ Thorough, free online consultations by licensed physicians We carefully review your medical history and listen to your concerns to decide whether a prescription is suitable. If a prescription cannot be issued, there is no charge—feel free to consult us.
✔️ All steps—from booking to delivery—done on your smartphone There’s no need to visit a clinic. You can complete everything from your phone and receive medication as soon as the next day, without disrupting your routine.
✔️ Bilingual doctors available elife has doctors fluent in both Japanese and English. Language barriers are not a concern.
✔️ Ongoing support throughout treatment Our support doesn’t end with the prescription. For medical concerns, consult the doctor. For service or account-related questions, our support team is always here to help.
✔️ Full privacy protection Everything is handled online. Medications are shipped in discreet packaging to ensure privacy—even within your household.
This exclusive plan is designed to provide a seamless start to your treatment journey. Please review the following details carefully.
[ Registration Details ] This offer covers the special introductory rate for your first month of treatment. Please note that purchasing this plan does not trigger immediate medication delivery. To receive your prescription, you must complete a separate online medical consultation after registration.
[ How it Works ] Once you register for this plan, we will email you instructions for your online consultation along with your exclusive eCoupon code. Simply click on the link inside the email to book your consultation, and automatically apply the eCoupon. Your medication will be shipped to your home following a physician’s evaluation and prescription.
[ Expiration Date ] This offer is valid for 90 days from the date of purchase. Please be aware that the discount will expire after 90 days and can no longer be applied to your treatment.
[ Refunds & Cancelations ] Once purchased, an ePass is generally non-refundable except where required by applicable law. However, if a physician determines during the consultation that a prescription is not appropriate and does not issue a prescription, the full amount paid will be refunded. Requests to cancel an ePass or obtain a refund due to a change of mind or other customer-related reasons cannot be accommodated, even if the physician consultation has not yet taken place.
[ Additional Terms ] For plans offering a discounted introductory rate compared to the standard price, a minimum number of required orders may apply as a condition of the discount. If you cancel your subscription before reaching the required minimum orders, the difference between the standard price and the discounted price will be charged to your registered credit card upon cancellation. Please refer to this page for details on the minimum required orders, initial price, and standard price for this plan. However, if subscription fulfillment becomes unavailable due to product out-of-stock issues or other circumstances attributable to us or our affiliated providers, this price difference will not be charged. Cancellations must be processed via "Manage Subscription" on your My Page at least 2 days prior to your next billing date. (If a "standard price" is not explicitly specified, the price for the second month/second order onward will be used to calculate the price difference. If you cannot find this information, please contact customer support.)
For more information, please refer to our User Guide.
A. No. After you purchase the ePass, an online medical consultation with a doctor is required. Your medication will be shipped only after the doctor approves your prescription.
Q. If I experience side effects, can I cancel?
A. Yes, absolutely. Even if you are on a subscription plan, if side effects occur and the doctor determines that continuing treatment is not safe, we will promptly process a cancellation. Your safety is our top priority.